The PROTECT team spans experts across multiple backgrounds, institutions, and career stages.
Investigators

Adam Arkin
Principal InvestigatorUniversity of California, Berkeley
Adam Arkin is a distinguished researcher specializing in microbiology and bioengineering,
with extensive experience leading multidisciplinary teams.

Karsten B. Zengler
Co-investigatorUniversity of California, San Diego
Karsten Zengler, a Professor at UC San Diego with over 20 years of experience in microbiology and systems biology, is a pioneer in community systems biology and high-throughput microbial cultivation, with a focus on host–microbe interactions, quantitative omics, and microbiome roles in health and disease.

Victor Nizet
Co-investigatorUniversity of California, San Diego
Victor Nizet, a Distinguished Professor of Pediatrics, focuses on bacterial pathogenesis and the innate immune system—particularly streptococcal and staphylococcal infections—and collaborates with biotech partners to develop novel antibiotic and immune-based therapies.

Douglas Conrad
Co-investigatorCleveland Clinic, Cleveland
Douglas Conrad, Professor of Medicine and Director of Adult Cystic Fibrosis, specializes in airway microbiome research, focusing on the integration of metagenomic, metabolomic, and genomic data with clinical phenotypes in cystic fibrosis.

Fatemah Askarian
Co-investigatorUniversity of California, San Diego
Fatemeh Askarian’s research focuses on host–pathogen interactions, combining microbial and host-based approaches to study the molecular pathogenesis of multi-drug resistant infections. In the PROTECT project, she leads in vivo translational efforts to advance clinical applications.

Jacob Hilzinger
Co-investigatorUniversity of California, San Diego
Jacob Hilzinger, an expert in microbial physiology, systems biology, and synthetic biology, applies genetic and systems-level tools to understand and engineer microbes while overseeing probiotic formulation, tissue-culture platform development, translational scoring of synbiotic products, and related business development efforts.

Kelsey Hern
Co-investigatorNorthwestern University, Chicago
Kelsey Hern, who holds a PhD in Microbiology from UC Berkeley, is a co-investigator on PROTECT, where she leads efforts in non-invasive engraftment monitoring and oversees scaling and early manufacturing to support therapeutic development for respiratory conditions.

Patricia Lenhart-Pendergrass
Co-investigatorUniversity of California, San Diego
Patricia M. Lenhart-Pendergrass, an Assistant Adjunct Professor specializing in pediatric pulmonology, researches infections in cystic fibrosis and leads patient sampling efforts for the PROTECT project.